Issued & Pending Patents

Issued & Pending Patents


1.  Modified Compstatin with Improved Stability and Binding Properties (Thioether). Type: Application. Issued: April 24, 2014. Inventors: J.D. Lambris and W. van der Donk. Link

2.  Complement-Mediated Thrombophilic Assay. Type: Grant (US Patent #8563259). Issued: October 22, 2013.
Inventors: J.D. Lambris and K. Ritis. Link  

3.  Compstatin Analogs with Improved Pharmacokinetic Properties. Type: Application. Issued: June 11, 2015. Inventors: J.D. Lambris, H. Qu, and D. Ricklin. Link  

4.  Complement Inhibitors as Therapeutic Agents for Treatment of Cancer. Type: Application. Issued: February 24, 2011.
Inventors: J.D. Lambris and M. Markiewski. Link  

5.  Complement Inhibitors for Treatment of Injury from Intracebral Hemorrhage. Type: Application. Issued: October 20, 2011.
Inventors: J.D. Lambris and S.E. Connolly. Link  

6.  Compositions and Methods for Inhibiting Inducible T Cell Kinase (ITK) and Treating Asthma and Bronchial Inflammations. Type: Application. Issued: November 11, 2010.
Inventors: K. Tsoukas and J.D. Lambris. Link  

7.  Compstatin Analogs with Improved Activity. Type: Grant (US Patent #8883413). Issued: November 11, 2014. Inventors: J.D. Lambris. Link  

8.  Compstatin Analogs with Improved Activity. Type: Application. Issued: June 11, 2015. Inventors: J. D. Lambris. Link  

9.  Compstatin Analogs with Improved Activity. Type: Grant (US Patent #7989589). Issued: August 2, 2011.
Inventors: J.D. Lambris. Link  

10.  Factor H Binding Peptides and Uses Thereof. Type: Grant (US Patent #8962795). Issued: February 24, 2015. Inventors: J. D. Lambris. Link  

11.  Factor H-Based Complement Inhibitor.
Inventors: J.D. Lambris, D. Ricklin, and C.Q. Schmidt.  

12.  Method of Inhibiting Biomaterial-Induced Procoagulant Activity Using Complement Inhibitors. Type: Grant (US Patent #8445190). Issued: May 21, 2013.
Inventors: J.D. Lambris and K. Ritis. Link  

13.  Method of Reducing Tissue Loss in Pancreatic Islet Cell Transplantation . Type: Application. Issued: January 13, 2011.
Inventors: J.D. Lambris, O. Korsgren, and B. Nillson. Link  

14.  Method of Treating Respiratory Acute Distress Syndrome. Type: Application. Issued: June 16, 2011.
Inventors: J.D. Lambris and K. Ritis. Link  

15.  Methods of Treating or Preventing Periodontitis and Diseases Associated with Periodontitis. Type: Application. Issued: December 26, 2013.
Inventors: G. Hajishengallis and J.D. Lambris. Link  

16.  Methods of Treating or Preventing Periodontitis and Diseases Associated with Periodontitis. Type: Application. Issued: February 7, 2013.
Inventors: G. Hajishengallis and J.D. Lambris. Link  

17.  Modified Compstatin with Peptide Backbone and C-Terminal Modifications. Type: Grant (US Patent # 8946145)Issued: July 23, 2015. Inventors: J.D. Lambris and H. Qu. Link  

18.  Peptides for Inhibition of Herpes Simplex Virus Entry. Type: Grant (US Patent #6699481). Issued: March 2, 2004. Inventors: J.D. Lambris, M.R. Sarrias, G.H. Cohen, P.G. Spear, and R.I. Mongomery. Link  

19.  Peptides for Inhibition of Herpes Simplex Virus Entry. Type: Application. Issued: December 23, 2004.
Inventors: J.D. Lambris, M.R. Sarrias, G.H. Cohen, R.J. Eisenberg, P.G. Spear, R.I. Montgomery. Link

20.  Peptides which Inhibit Complement Activation. Type: Grant (US Patent #6319897). Issued: November 20, 2001. Inventors: J.D. Lambris and A. Sahu. Link  

21.  Potent Compstatin Analogs. Type: Grant (US Patent #7888323). Issued: February 15, 2011.
Inventors: J.D. Lambris and M. Katragadda. Link  

22.  Potent Compstatin Analogs. Type: Grant (US Patent #7888323). Issued: February 15, 2011.
Inventors: J.D. Lambris and M. Katragadda. Link

23.  Regulator of Complement Activation and Uses Thereof . Type: Application. Issued: April 23, 2015. Inventors: J.D. Lambris, C. Schmidt, and D. Ricklin. Link  

24.  Secreted Staphylococcus Aureus Proteins and Peptides for Use in Inhibiting Activation of the Complement System. Type: Application. Issued: February 24, 2011.
Inventors: J.D. Lambris and B.V. Geisbrecht. Link

25.  Structure of C3bB-factor D Complex and Use for Rational Drug Design.
Inventors: J. D. Lambris, D. Ricklin, F. Forneris, and P. Gros.  

26.  Structure of Compstatin-C3 Complex and Use for Rational Drug Design. Type: Grant (US Patent #8442776). Issued: May 14, 2013.
Inventors: J.D. Lambris, B.J.C. Janssen, and P. Gros. Link  

27.  Treatment of Colon Cancer Using Complement Inhibitors. Type: Application. Issued: August 7, 2014. Inventors: J.D. Lambris, J. Nadeau, S. Doerner, and N. D. Berger. Link  

28.  Treatment of Sepsis Using Complement Inhibitors. Type: Application. Issued: February 28, 2013.
Inventors: J.D. Lambris, F. B. Taylor, F. Lupu, and G. Kinasewitz. Link  


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